Production of germ cell-deficient salmonids bydead endgene knockdown, and their use as recipients for germ cell transplantation
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چکیده
منابع مشابه
I-18: Avian Chimeras and Germ Cell Migration
Background: In avian species, the germ line stem cell population arises outside of the embryonic gonad and proceeds on a circuitous migration to the germinal epithelium. Specifically, in the avian embryo, the process of germ line stem cell migration proceeds through a series of active and passive migratory phases. The germline stem cells or primordial germ cells (PGCs) located in the epiblast o...
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The efficiency of germ cell transplantation, the procedure of transferring germ cells from a donor male into the testes of recipient males, can be greatly increased by reduction of endogenous germ cells in recipient animals. To develop effective methods for suppression of endogenous spermatogenesis in potential pig and goat recipients, we either administered busulfan to pregnant sows or irradia...
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ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2016
ISSN: 1040-452X
DOI: 10.1002/mrd.22625